HA5 Hydra Collagen Replenish and Restore Hydrator: HA5® Hydra Collagen Replenish + Restore Hydrator is SkinMedica's latest evolution in hydrator technology. Hydrators actively restore endogenous hyaluronic acid production deep within the skin's layer, and this lightweight cream to water serum is powered by HA5® technology with immediate results that lasts 48 hours. Features 5 forms of Hyaluronic Acid + Hydra Collagen Complex for immediate hydration, as well as SkinMedica's proprietary Advanced VITISENSCE® Technology for long-term hydration that targets existing collagens within the skin to boost hydration naturally. Clinically proven to improve hydration and skin health by improving the skin barrier and skin's water-holding capacity. The result? Visibly plumper, dewy, hydrated, younger-looking skin. Age Defense Retinol Complex 1.0: SkinMedica's Age Defense Retinol Complex 1.0 enhances the skin's appearance to promote a smoother, rejuvenated complexion. Formulated for skin types pre-conditioned to retinol treatments, it minimizes the appearance of age spots and wrinkles. It also improves elasticity and works effectively to visibly reduce acne scars. With continued use, faster cell renewal is encouraged.